Mississippi State Department of Health

Treatment for COVID-19 Infection


If you test positive for COVID-19 and may be at higher risk for severe illness, ask your doctor about treatment to prevent serious illness and hospitalization.

Healthcare Provider Resources

What treatments are available for COVID-19?

Oral Antivirals

Ages 12 and up are eligible for treatment with Paxlovid.

Oral antiviral therapies Paxlovid (Pfizer) and molnupiravir (Merck) are products authorized by the FDA for treatment of COVID-19. These therapies require a prescription from a licensed healthcare provider. Talk to your healthcare provider or pharmacist to see whether an oral antiviral is the right option for you.

How they work: Oral antiviral medications work by targeting specific proteins on the SARS-CoV-2 virus to help prevent the virus replicating within the body. It is important that the oral antiviral is started within 5 days of the start of symptoms.

Monoclonal Antibodies

Monoclonal antibodies, or mAbs, are made in a laboratory to fight a particular infection, based on natural antibodies against COVID-19.

How they work: Your body naturally makes antibodies to fight infection. However, your body may not have antibodies designed to recognize a new virus like the one that causes COVID-19.

There are no monoclonal antibodies currently authorized in the U.S. for treatment if you have COVID-19. There is one mAb product designed for prevention of COVID-19, however, if you are currently healthy.


Evusheld is a monoclonal antibody use for prevention in individuals with weakened immune systems, such as cancer treatment patients.

Evusheld is currently not authorized in the U.S for prevention of COVID-19

Who can receive treatment?

People who test positive for COVID-19 with mild to moderate symptoms who are at higher risk for developing more serious COVID-19 symptoms may be eligible for oral antiviral treatment, depending on their health history and exposure to COVID-19, and how long they've had symptoms of COVID-19.

Cost: The oral antivirals Paxlovid and molnupiravir are provided free from the federal government. Coverage of fees for administration or dispensing depends on your specific health insurance policy.

Where can I receive treatment?

These therapies require a prescription by a licensed and authorized provider. Patients should coordinate with their healthcare provider prior to contacting a location to receive these therapies.

Locate Medications

Use this interactive map to locate a facility that can provide medication for COVID-19.

Links referenced on this page
Healthcare Provider Resources    http://msdh.ms.gov/msdhsite/index.cfm/14,0,420,694,html ok
Oral Antiviral Therapeutics: Information for healthcare professionals    http://msdh.ms.gov/msdhsite/index.cfm/14,0,420,694,html ok
View this locator full-screen    https://app.powerbigov.us/view?r=eyJrIjoiMzkxZDYzNmUtYTg3Ni00YzljLWFmODctMDg1Njc5MzE2MjU1IiwidCI6IjU1OTA0MmRjLThiZjAtNGQ4Ni05ZmMwLWZiZjRjNzUwM2M3OSJ9

Find this page at http://msdh.ms.gov/msdhsite/index.cfm/index.cfm

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